You could use something like this - bind the OnChange event of each field to this method:
function OnChange() { Xrm.Page.getAttribute("new_multi").setValue(null); var message = ""; if (Xrm.Page.getAttribute("new_field1").getValue()) { message = "text1"; } if (Xrm.Page.getAttribute("new_field2").getValue()) { if (message != null) { message += "\r\n"; } message += "text2"; } if (Xrm.Page.getAttribute("new_field3").getValue()) { if (message != null) { message += "\r\n"; } message += "text3"; } //Add more fields as required Xrm.Page.getAttribute("new_multi").setValue(message); }